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About this Research Topic

Manuscript Submission Deadline 08 January 2023

Imaging offers the opportunity to further understand cancer at the macroscopic and microscopic levels. At the macroscopic level, routine clinical imaging such as magnetic resonance and computed tomography have the potential to identify features capturing the heterogeneity of the entire tumor burden, in addition to providing insights regarding the tumor environment. At the microscopic level, high-resolution methods combined with the ability to grow organoids with high efficiency from healthy adult stem cells provide complementary information regarding the underlying biology and the ability to study the mechanisms of cancer, tumor pathogenesis, and response to treatments in incredible detail.

This Research Topic particularly focuses on the imaging of colorectal cancer, with the goal being to identify imaging biomarkers predictive of therapy resistance. The research topic is very broad with respect to the imaging modalities used to provide insights, though studies introducing novel imaging approaches and novel theranostic probes are especially valued.

All study types are welcome, including but not limited to research articles, observational studies, meta-analyses, reviews, or case reports/series.

Sub-themes for this research topic include but are not limited to:

- Prognostic biomarkers for treatment response using 3D tomographic clinical imaging.

- Fluorescence optical imaging and localized surface plasmon resonance for theranostic probe imaging.

- Automated tumor staging using clinically available imaging.

- Laser-scanning endomicroscopy techniques for in vivo tumor characterization or in situ organoid characterization.

Keywords:Colorectal cancer, Gastroenterology, Cancer, In vivo, In situ


Important Note:All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Imaging offers the opportunity to further understand cancer at the macroscopic and microscopic levels. At the macroscopic level, routine clinical imaging such as magnetic resonance and computed tomography have the potential to identify features capturing the heterogeneity of the entire tumor burden, in addition to providing insights regarding the tumor environment. At the microscopic level, high-resolution methods combined with the ability to grow organoids with high efficiency from healthy adult stem cells provide complementary information regarding the underlying biology and the ability to study the mechanisms of cancer, tumor pathogenesis, and response to treatments in incredible detail.

This Research Topic particularly focuses on the imaging of colorectal cancer, with the goal being to identify imaging biomarkers predictive of therapy resistance. The research topic is very broad with respect to the imaging modalities used to provide insights, though studies introducing novel imaging approaches and novel theranostic probes are especially valued.

All study types are welcome, including but not limited to research articles, observational studies, meta-analyses, reviews, or case reports/series.

Sub-themes for this research topic include but are not limited to:

- Prognostic biomarkers for treatment response using 3D tomographic clinical imaging.

- Fluorescence optical imaging and localized surface plasmon resonance for theranostic probe imaging.

- Automated tumor staging using clinically available imaging.

- Laser-scanning endomicroscopy techniques for in vivo tumor characterization or in situ organoid characterization.

Keywords:Colorectal cancer, Gastroenterology, Cancer, In vivo, In situ


Important Note:All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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